The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies

Mutations affecting segment number and polarity in Drosophila

Christiane Nüsslein‐Volhard, Eric Wieschaus · Nature · 1980 · 4.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek et al. · Science · 1997 · 3.9K citations

Medicine, Molecular Biology, Oncology +17

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

Osamu Tetsu, Frank McCormick · Nature · 1999 · 3.6K citations

Medicine, Cell Biology, Oncology +14

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

Vladimír Kořínek, Nick Barker, Patrice J. Morin et al. · Science · 1997 · 3.3K citations

Medicine, Cancer Biology, Molecular Genetics +17

Functional interaction of β-catenin with the transcription factor LEF-1

Jürgen Behrens, Jens Peter von Kries, Michael Kühl et al. · Nature · 1996 · 2.9K citations

Life Sciences, Cell Biology, Molecular Biology +8