Dynorphin(1–13), a long-lasting inhibitor of opiate receptor binding

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Medicine, Medicinal Chemistry, Pharmacology +13

Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

Charles Chavkin, Iain F. James, Avram Goldstein · Science · 1982 · 1.2K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Possible regulatory role of dynorphin on morphine- and beta-endorphin-induced analgesia.

F. Cankat Tulunay, M.F. Jen, J.K. Chang et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 172 citations

Medicine, Pharmacology, Neuropharmacology +16

Behavioral effects and in vivo degradation of intraventricularly administered dynorphin-(1-13) and D-Ala2-dynorphin-(1-11) in rats

Barbara H. Herman, Frances M. Leslie, Avram Goldstein · Life Sciences · 1980 · 127 citations

Life Sciences, Neuroscience, Pharmacology +12

The preference of putative pro-enkephalins for different types of opiate receptors

Michael Wüster, Patrizia Rubini, Rüdiger Schulz · Life Sciences · 1981 · 114 citations

Medicine, Pharmacology, Neuropharmacology +12