Concepedia
The International Journal of Neuropsychopharmacology · 2014 · 38 citations · 29 references
Open access
These findings support the utility of small animals and quantitative PET in the development of drugs targeting NK-1 receptors.
29
Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors
Mark S. Kramer, Neal R. Cutler, John P. Feighner et al. · Science · 1998 · 1.1K citations
Psychotropic Medication, Psychopharmacology, Antidepressant Activity +16
Comparison of Methods for Analysis of Clinical [<sup>11</sup>C]Raclopride Studies
Adriaan A. Lammertsma, C. J. Bench, S.P. Hume et al. · Journal of Cerebral Blood Flow & Metabolism · 1996 · 459 citations
Performance evaluation of the microPET focus: a third-generation microPET scanner dedicated to animal imaging.
Yuan‐Chuan Tai, A. Ruangma, Douglas J. Rowland et al. · PubMed · 2005 · 398 citations
Lack of Efficacy of the Substance P (Neurokinin1 Receptor) Antagonist Aprepitant in the Treatment of Major Depressive Disorder
Martin B. Keller, Stuart Montgomery, William A. Ball et al. · Biological Psychiatry · 2005 · 287 citations
Psychoactive Drug, Psychiatry, Addiction +12
Demonstration of the Efficacy and Safety of a Novel Substance P (NK1) Receptor Antagonist in Major Depression
Mark S. Kramer, Andrew Winokur, Jeffrey E. Kelsey et al. · Neuropsychopharmacology · 2003 · 258 citations
Psychiatry, Functional Selectivity, Medicine +14