Concepedia

Temocaprilat, a Novel Angiotensin-Converting Enzyme Inhibitor, is Excreted in Bile via an ATP-dependent Active Transporter (cMOAT) That is Deficient in Eisai Hyperbilirubinemic Mutant Rats (EHBR)

Hitoshi Ishizuka, K Konno, Hideo Naganuma, K Sasahara, Yukinori Kawahara, Kayoko Niinuma, Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics · 1997 · 86 citations · 41 references

Open access

References

41

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

Inka Leier, Gabriele Jedlitschky, Ulrike Buchholz et al. · Journal of Biological Chemistry · 1994 · 856 citations · Full text

Medicine, Biochemistry, Pharmacology +14

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

Coen C. Paulusma, Piter J. Bosma, Guido J.R. Zaman et al. · Science · 1996 · 832 citations

Medicine, Genetics, Molecular Genetics +17

cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats

Markus W. Büchler, Jörg König, Manuela Brom et al. · Journal of Biological Chemistry · 1996 · 646 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

Michael Müller, Coby Meijer, G J Zaman et al. · Proceedings of the National Academy of Sciences · 1994 · 622 citations · Full text

Medicine, Oncology, Pharmacology +17

BindingDB Entry 50042057: Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump.

PubMed · 2013 · 576 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15