Association of single nucleotide polymorphisms of ABCB1, OPRM1 and COMT with pain perception in cancer patients

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity <i>in</i> <i>vivo</i>

Sven Hoffmeyer, Oliver Burk, Oliver von Richter et al. · Proceedings of the National Academy of Sciences · 2000 · 2.4K citations

Medicine, Molecular Genetics, Pharmacology +15

Genetic basis for individual variations in pain perception and the development of a chronic pain condition

Luda Diatchenko, Gary D. Slade, Andrea G. Nackley et al. · Human Molecular Genetics · 2004 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Kinetics of Human Soluble and Membrane-Bound Catechol O-Methyltransferase: A Revised Mechanism and Description of the Thermolabile Variant of the Enzyme

Timo Lotta, Jukka Vidgren, Carola Tilgmann et al. · Biochemistry · 1995 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +6

COMT <i> val ¹⁵⁸ met </i> Genotype Affects µ-Opioid Neurotransmitter Responses to a Pain Stressor

Jon-Kar Zubieta, Mary M. Heitzeg, Yolanda R. Smith et al. · Science · 2003 · 1.1K citations

Life Sciences, Genetics, Neuroscience +17

Human Catechol- <i>O</i> -Methyltransferase Haplotypes Modulate Protein Expression by Altering mRNA Secondary Structure

Andrea G. Nackley, Svetlana A. Shabalina, Inna E. Tchivileva et al. · Science · 2006 · 853 citations

Life Sciences, Genetics, Molecular Genetics +17