The use of generic surrogate peptides for the quantitative analysis of human immunoglobulin G1 in pre-clinical species with high-resolution mass spectrometry

Triple quadrupole mass spectrometry for direct mixture analysis and structure elucidation

Richard A. Yost, Christie G. Enke · Analytical Chemistry · 1979 · 329 citations

Natural Sciences, Chemistry, Analytical Chemistry +10

The Amino Acid Following an Asn-X-Ser/Thr Sequon Is an Important Determinant of N-Linked Core Glycosylation Efficiency

J. L. Mellquist, Lakshmi Kasturi, Steven L. Spitalnik et al. · Biochemistry · 1998 · 275 citations

Life Sciences, Biochemistry, Molecular Biology +14

Identification and Characterization of Deamidation Sites in the Conserved Regions of Human Immunoglobulin Gamma Antibodies

Dirk Chelius, Douglas S. Rehder, Pavel V. Bondarenko · Analytical Chemistry · 2005 · 263 citations

Life Sciences, Biochemistry, Molecular Biology +17

Towards Absolute Quantification of Therapeutic Monoclonal Antibody in Serum by LC−MS/MS Using Isotope-Labeled Antibody Standard and Protein Cleavage Isotope Dilution Mass Spectrometry

Olivier Heudi, Samuel Barteau, Dieter Zimmer et al. · Analytical Chemistry · 2008 · 230 citations

Pharmacy, Biochemistry, Immunology +17

General LC-MS/MS Method Approach to Quantify Therapeutic Monoclonal Antibodies Using a Common Whole Antibody Internal Standard with Application to Preclinical Studies

Hongyan Li, Robert Ortiz, Linh T. Tran et al. · Analytical Chemistry · 2012 · 192 citations

Pharmacy, Immunology, Pharmacokinetics +17