Towards Absolute Quantification of Therapeutic Monoclonal Antibody in Serum by LC−MS/MS Using Isotope-Labeled Antibody Standard and Protein Cleavage Isotope Dilution Mass Spectrometry

Olivier Heudi, Samuel Barteau, Dieter Zimmer, +5

Analytical Chemistry

Towards Absolute QuantificationImmunocytochemical TechniqueImmunologyBiological Mass SpectrometryPathology +23

New Microfluidic-Based Sampling Procedure for Overcoming the Hematocrit Problem Associated with Dried Blood Spot Analysis

Luc Alexis Leuthold, Olivier Heudi, Julien Déglon, +5

Analytical Chemistry

ImmunohematologyEngineeringAnalytical MicrosystemsBiomedical EngineeringMedical Instrumentation +19

Antibiotic and Hemolytic Activity of a β²/β³ Peptide Capable of Folding into a 12/10‐Helical Secondary Structure

Per I. Arvidsson, Neil S. Ryder, H. Weiss, +3

ChemBioChem

Peptide EngineeringMolecular BiologyPeptide SciencePeptide TherapeuticsPeptide Chemistry +14

<i>In vitro</i> blood distribution and plasma protein binding of the tyrosine kinase inhibitor imatinib and its active metabolite, CGP74588, in rat, mouse, dog, monkey, healthy humans and patients with acute lymphatic leukaemia

Olivier Kretz, H. Weiss, M. Schumacher

British Journal of Clinical Pharmacology

Removal of anti-Galα1,3Gal xenoantibodies with an injectable polymer

Andreas Katopodis, Richard G. Warner, Rudolf O. Duthaler, +14

Journal of Clinical Investigation

GlycobiologyImmunologyAlphagal BindingImmunotherapyProtein Purification +15

Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents

Terence O’Reilly, Paul M.J. McSheehy, R. Kawai, +7

Cancer Chemotherapy and Pharmacology

OncologyMedicinePharmacotherapyAnti-cancer AgentComparative Pharmacokinetics +4

Intestinal Lymphatic Transport Enhances the Post-Prandial Oral Bioavailability of a Novel Cannabinoid Receptor Agonist Via Avoidance of First-Pass Metabolism

Natalie L. Trevaskis, David M. Shackleford, William N. Charman, +6

Pharmaceutical Research

Cannabis UseFirst-pass MetabolismIntestinal Lymphatic TransportPost-prandial Oral BioavailabilityFunctional Selectivity +6

Mitogenic activity and immunological properties of bolesatine, a lectin isolated from the mushroom Boletus satanas Lenz

Frederico Licastro, Maria Morini, Olivier Kretz, +3

International Journal of Biochemistry

BiologyMitogenic ActivityImmunologyImmunological PropertiesMushroom Boletus +2

Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation

Nenad Manevski, Piet Swart, Kamal K. Balavenkatraman, +13

Drug Metabolism and Disposition

Characterization of bolesatine, a toxic protein from the mushroom Boletus satanas Lenz and it's effects on kidney cells

Olivier Kretz, E.E. Creppy, G. Dirheimer

Toxicology

BiochemistryNatural SciencesMedicineToxic ProteinToxicology +4