Learning the parts of objects by non-negative matrix factorization

Daniel D. Lee, H. Sebastian Seung

Nature

Non-negative Matrix FactorizationMachine VisionImage AnalysisData ScienceMachine Learning +9

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

Charity W. Law, Yunshun Chen, Wei Shi, +1

Genome biology

Comprehensive molecular characterization of clear cell renal cell carcinoma

Nature

Cancer ResearchUrologyGenitourinary CancerKidney ResearchComprehensive Molecular Characterization +12

Cancer Cell Metabolism: Warburg and Beyond

Peggy P. Hsu, David M. Sabatini

Cell

Malignant DiseaseMedicineCancer Cell MetabolismCancer Cell BiologyCancer Biology +5

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

Arun Sreekumar, Laila Poisson, Thekkelnaycke M. Rajendiran, +23

Nature

MedicineMetabolomic ProfilingCancer GenomicsPotential RoleCancer Biology +8

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton, +14

Nature

Oncogenic AgentOncogene-induced Nrf2 TranscriptionReactive Oxygen SpecieMedicineCell Biology +3

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

Jaekyoung Son, Costas A. Lyssiotis, Haoqiang Ying, +15

Nature

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

Christian M. Metallo, Paulo A. Gameiro, Eric L. Bell, +11

Nature

BiochemistryRedox RegulatorHypoxia (Medicine)MetabolismMedicine +3

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Cosimo Commisso, Shawn M. Davidson, Rengin G. Soydaner-Azeloglu, +11

Nature

Protein FunctionSignal TransductionRas-transformed CellsMedicineNatural Sciences +9

A flexible R package for nonnegative matrix factorization

Renaud Gaujoux, Cathal Seoighe

BMC Bioinformatics