Concepedia

Selectivity of the Multidrug Resistance Modulator, LY335979, for P-Glycoprotein and Effect on Cytochrome P-450 Activities

Anne H. Dantzig, Robert L. Shepard, K L Law, Linda B. Tabas, Susan E. Pratt, Jennifer S. Gillespie, S N Binkley, Michael T. Kuhfeld, James J. Starling, Steven Wrighton

Journal of Pharmacology and Experimental Therapeutics · 1999 · 179 citations · 27 references

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27

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3.1K citations

, , +16

Goodman and Gilman's The Pharmacological Basis of Therapeutics

Robert C. Hastings · JAMA · 1996 · 2.4K citations

, , +6

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

Marcel Kool, Marcel de Haas, George L. Scheffer et al. · PubMed · 1997 · 898 citations

, , +15

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

Inka Leier, Gabriele Jedlitschky, Ulrike Buchholz et al. · Journal of Biological Chemistry · 1994 · 856 citations · Full text

, , +14

Drug Resistance and ATP-Dependent Conjugate Transport Mediated by the Apical Multidrug Resistance Protein, MRP2, Permanently Expressed in Human and Canine Cells

Yunhai Cui, Jörg König, Ulrike Buchholz et al. · Molecular Pharmacology · 1999 · 681 citations

, , +14