PEGylation of 6-amino-6-deoxy-curdlan for efficient in vivo siRNA delivery

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.1K citations

Specific Genetic Interference, Natural Sciences, Genetics +9

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.3K citations

Natural Sciences, Rna Splicing, Rna Biology +9

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Lydia Alvarez‐Erviti, Yiqi Seow, HaiFang Yin et al. · Nature Biotechnology · 2011 · 4.7K citations

Cell-based Drug Delivery, Nanomedicine, Systemic Injection +9

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Mark E. Davis, Jonathan E. Zuckerman, Chung Hang Jonathan Choi et al. · Nature · 2010 · 2.5K citations · Full text

Targeted Nanoparticles, Nanomedicine, Nanotherapeutics +9

Nanocapsule formation by interfacial polymer deposition following solvent displacement

Hatem Fessi, F. Puisieux, J.P. Devissaguet et al. · International Journal of Pharmaceutics · 1989 · 2.2K citations

Materials Science, Engineering, Nanomaterials +4