Age-dependent effects in fathead minnows from the anti-diabetic drug metformin

Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000:  A National Reconnaissance

Dana W. Kolpin, Edward T. Furlong, Michael T. Meyer et al. · Environmental Science & Technology · 2002 · 7.9K citations

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Role of AMP-activated protein kinase in mechanism of metformin action

Gaochao Zhou, Robert P. Myers, Ying Li et al. · Journal of Clinical Investigation · 2001 · 5.4K citations

Life Sciences, Endocrinology, Pharmacology +16

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

Mark R. Owen, E. Doran, Andrew P. Halestrap · Biochemical Journal · 2000 · 2.1K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

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Life Sciences, Neuroscience, Physiology +14

Hypothalamic mTOR Signaling Regulates Food Intake

Daniela Cota, Karine Proulx, Kathi A. Blake Smith et al. · Science · 2006 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +17