Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes but Different Regulatory Gene Sets

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.8K citations

Developmental Biology, Autoimmune Disease, Lymphocyte Development +13

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

Marc Veldhoen, Richard J. Hocking, Christopher J. Atkins et al. · Immunity · 2006 · 3.6K citations · Full text

Inflammation, Cytokine, Lymphocyte Development +9

CD69 acts downstream of interferon-α/β to inhibit S1P1 and lymphocyte egress from lymphoid organs

Lawrence R. Shiow, David B. Rosen, Naděžda Brdičková et al. · Nature · 2006 · 1.1K citations

Inflammation, Adaptive Immune System, Viral Immunity +14

Prevalence of cardiovascular risk factors in patients with psoriasis

Andrea L. Neimann, Daniel B. Shin, Xingmei Wang et al. · Journal of the American Academy of Dermatology · 2006 · 1K citations

Medicine, Clinical Dermatology, Cardiovascular Risk Factors +4

Psoriasis Is Common, Carries a Substantial Burden Even When Not Extensive, and Is Associated with Widespread Treatment Dissatisfaction

Robert S. Stern, Tamar Nijsten, Steven R. Feldman et al. · Journal of Investigative Dermatology Symposium Proceedings · 2004 · 734 citations · Full text

Psoriatic Arthritis, Clinical Dermatology, Substantial Burden +3