Concepedia

Carbon Monoxide-Releasing Molecule-2 Reduces Intestinal Epithelial Tight-Junction Damage and Mortality in Septic Rats

Shulong Zhang, Shuyun Zheng, Xin Wang, Qiankun Shi, Xiang Wang, Shou-Tao Yuan, Guozheng Wang, Zhenling Ji

PLoS ONE · 2015 · 39 citations · 32 references

Open access

Abstract

Our data strongly suggest that CORM-2 could be a potential therapeutic reagent for sepsis by suppressing inflammation, restoring intestinal epithelial barrier and reducing mortality.

References

32

Intestinal Mucosal Lesion in Low-Flow States

Chu-Jeng Chiu · Archives of Surgery · 1970 · 1.8K citations

Inflammation, Low-flow States, Fluid Mechanics +14

Protective effects of C5a blockade in sepsis

Boris J. Czermak, Vidya Sarma, Carl L. Pierson et al. · Nature Medicine · 1999 · 404 citations

Inflammation, Immunology, Sepsis +4

Intestinal barrier failure during experimental necrotizing enterocolitis: protective effect of EGF treatment

Jessica A. Clark, S Doelle, Melissa D. Halpern et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2006 · 258 citations

Immunology, Gastroenterology, Pathology +16

The Heme Oxygenase-1/Carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-1

Xiao Mei Wang, Hong Pyo Kim, Kiichi Nakahira et al. · The Journal of Immunology · 2009 · 223 citations · Full text

Inflammatory Lung Disease, Lung Inflammation, Immunology +19

Reciprocal Regulation of the Junctional Proteins Claudin-1 and Connexin43 by Interleukin-1β in Primary Human Fetal Astrocytes

Heather S. Duffy, Gareth John, Sunhee C. Lee et al. · Journal of Neuroscience · 2000 · 139 citations · Full text