Antimicrobial Agents and Chemotherapy · 2015 · 43 citations · 49 references
Life SciencesInfectious DiseasesMicrobiologyBacteriologyMedical MicrobiologyMicrobial GeneticsBacterial Disease EpidemiologyBacterial EpidemiologyBacterial InfectionsBacterial PathogenesisCarbapenem ResistancePathogen GenomicsCarbapenem Resistance PlasmidsCarbapenem Resistance SurveillanceCarbapenemase EnzymesEnterobacteriaceae DetectionExtended-spectrum Beta-lactamase Producing OrganismsKlebsiella Pneumoniae CarbapenemaseKlebsiella Pneumoniae ResistanceMolecular Typing Of Bacteria
In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.
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Identification of plasmids by PCR-based replicon typing
Alessandra Carattoli, Alessia Bertini, Laura Villa et al. · Journal of Microbiological Methods · 2005 · 2.3K citations
Sex and virulence in <i>Escherichia coli</i>: an evolutionary perspective
Thierry Wirth, Daniel Falush, Ruiting Lan et al. · Molecular Microbiology · 2006 · 2K citations · Full text