A General Method for Detecting and Sizing Large Plasmids

Barry Barton, G. Harding, Anthony J. Zuccarelli

Analytical Biochemistry

Sizing Large PlasmidsPathogen DetectionMicroscopyComputational BiologyDetection Technique +4

Beta-lactam antibiotic biosynthetic genes have been conserved in clusters in prokaryotes and eukaryotes.

D. J. Smith, Martin Burnham, John H. Bull, +7

The EMBO Journal

BiosynthesisAntimicrobial Resistance GeneAntibioticsMicrobial GeneticsBacteriology +6

Analysis of a commercially improved Penicillium chrysogenum strain series: involvement of recombinogenic regions in amplification and deletion of the penicillin biosynthesis gene cluster

Roger W. Newbert, Barry Barton, Philip Greaves, +2

Journal of Industrial Microbiology & Biotechnology

Five Additional Genes Are Involved in Clavulanic Acid Biosynthesis in <i>Streptomyces clavuligerus</i>

Susan E. Jensen, Ashish S. Paradkar, Roy H. Mosher, +5

Antimicrobial Agents and Chemotherapy

Genes Specific for the Biosynthesis of Clavam Metabolites Antipodal to Clavulanic Acid Are Clustered with the Gene for Clavaminate Synthase 1 in <i>Streptomyces clavuligerus</i>

Roy H. Mosher, Ashish S. Paradkar, Cecilia Anders, +2

Antimicrobial Agents and Chemotherapy

5S Clavam Biosynthetic Genes Are Located in Both the Clavam and Paralog Gene Clusters in Streptomyces clavuligerus

Kapil Tahlan, Cecilia Anders, Annie Wong, +8

Chemistry & Biology

BiologyBiosynthesisEngineeringStreptomyces ClavuligerusGenetics +10

Applications of Gene Replacement Technology to <i>Streptomyces clavuligerus</i> Strain Development for Clavulanic Acid Production

Ashish S. Paradkar, Roy H. Mosher, Cecilia Anders, +6

Applied and Environmental Microbiology

EngineeringGeneticsBacteriologyGene Replacement TechnologyBiosynthesis +18

ORF6 from the clavulanic acid gene cluster of <i>Streptomyces clavuligerus</i> has ornithine acetyltransferase activity

Nadia J. Kershaw, Heather J. McNaughton, Kirsty S. Hewitson, +7

European Journal of Biochemistry

β-Lactam synthetase: implications for β-lactamase evolution

Heather J. McNaughton, Jan E. Thirkettle, Zhihong Zhang, +4

Chemical Communications

EngineeringTheoretical Inorganic ChemistryChemistrySpectra-structure CorrelationProtein Synthesis +17

<i>Streptomyces clavuligerus</i> Has a Second Copy of the Proclavaminate Amidinohydrolase Gene

Susan E. Jensen, Annie Wong, Alison Griffin, +1

Antimicrobial Agents and Chemotherapy

EngineeringGeneticsNew Pah GeneEnzymatic ModificationBiosynthesis +14