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BIIB042, a novel γ-secretase modulator, reduces amyloidogenic Aβ isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer's disease

Neurodegenerative DiseasesAlzheimer's DiseaseBiochemistryPlaque PathologyMedicineDegenerative PathologyProtein MisfoldingNeuroscienceAging-associated DiseasePharmacologyMouse ModelNovel γ-Secretase Modulator