Cobalt Protoporphyrin Upregulates Cyclooxygenase-2 Expression Through a Heme Oxygenase-Independent Mechanism

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.5K citations

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

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ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

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Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

Tarek A. Samad, Kimberly A. Moore, Adam Sapirstein et al. · Nature · 2001 · 1.3K citations

Inflammation, Interleukin-1β-mediated Induction, Pain Syndrome +13

Toll-like receptor–mediated cytokine production is differentially regulated by glycogen synthase kinase 3

Michael Martin, Kunal Rehani, Richard S. Jope et al. · Nature Immunology · 2005 · 1.1K citations · Full text

Inflammation, Toll-like Receptors, Molecular Immunology +14