Concepedia

Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor

Aili L. Lazaar, Lucy Yang, Rebecca Boardley, Navin Goyal, Jonathan Robertson, Sandra Baldwin, David E. Newby, Ian B. Wilkinson, Ruth Tal‐Singer, Ruth J. Mayer,

British Journal of Clinical Pharmacology · 2015 · 171 citations · 30 references

DOIFull text

Open access

Abstract

GSK2256294 was well-tolerated and demonstrated sustained inhibition of sEH enzyme activity. These data support further investigation in patients with endothelial dysfunction or abnormal tissue repair, such as diabetes, wound healing or COPD.

References

30

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