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The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway

Ampk-sirt1/p300 PathwayChemoprevention StrategyMedicineNf-κb ActivationTumor SuppressorMetabolic SignalingPharmacologyCell BiologyCell SignalingP65 AcetylationCancer Research