Development of a Microscale Red Blood Cell-Shaped Pectin-Oligochitosan Hydrogel System Using an Electrospray-Vibration Method: Preparation and Characterization

Abstract

This system showed a significant potential not only for bioactive-agent delivery, especially to the lower gastrointestinal (GI) tract, but also as a three-dimensional niche for cell culture. In particular, the hydrogel microcapsule system could be used to create artificial red-blood-cells as well as blood substitutes.