CD8 T-Cell Expansion and Inflammation Linked to CMV Coinfection in ART-treated HIV Infection

Michael L. Freeman, Joseph C. Mudd, Carey L. Shive, Souheil-Antoine Younes, Soumya Panigrahi, Scott F. Sieg, Sulggi A. Lee, Peter W. Hunt, Leonard H. Calabrese, Sara Gianella,

Clinical Infectious Diseases · 2015 · 138 citations · 36 references

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Abstract

CMV infection is associated with higher CD8 T-cell counts, resultant lower CD4/CD8 ratios, and increased systemic inflammation in ART-treated HIV infection. CMV infection may contribute to risk for morbid outcomes in treated HIV infection.

References

36