Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents

Novel Benzofuran and Benzothiophene Biphenyls as Inhibitors of Protein Tyrosine Phosphatase 1B with Antihyperglycemic Properties

Michael S. Malamas, Janet Sredy, Christopher Moxham et al. · Journal of Medicinal Chemistry · 2000 · 210 citations · Full text

Benzofuran/benzothiophene Biphenyl Framework, Chemical Biology, Pharmaceutical Chemistry +18

Structure-based Design of a Low Molecular Weight, Nonphosphorus, Nonpeptide, and Highly Selective Inhibitor of Protein-tyrosine Phosphatase 1B

Lars Iversen, Henrik Sune Andersen, Sven Branner et al. · Journal of Biological Chemistry · 2000 · 173 citations · Full text

Ptp1b Knockout Mice, Low Molecular Weight, Biochemistry +12

PTP1B Inhibition and Antihyperglycemic Activity in the ob/ob Mouse Model of Novel 11-Arylbenzo[<i>b</i>]naphtho[2,3-<i>d</i>]furans and 11-Arylbenzo[<i>b</i>]naphtho[2,3-<i>d</i>]thiophenes

Jay Wrobel, Janet Sredy, Christopher Moxham et al. · Journal of Medicinal Chemistry · 1999 · 126 citations · Full text

Altmetric Attention Score, System Pharmacology, Experimental Pharmacology +21

2-(Oxalylamino)-Benzoic Acid Is a General, Competitive Inhibitor of Protein-tyrosine Phosphatases

Henrik Sune Andersen, Lars Iversen, Claus Jeppesen et al. · Journal of Biological Chemistry · 2000 · 119 citations · Full text

New Azolidinediones as Inhibitors of Protein Tyrosine Phosphatase 1B with Antihyperglycemic Properties

Michael S. Malamas, Janet Sredy, Iwan Gunawan et al. · Journal of Medicinal Chemistry · 2000 · 102 citations · Full text