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Discovery of a potent and selective agonist of the prostaglandin EP4 receptor

Xavier Billot, Anne Châteauneuf, Nathalie Chauret, Danielle Denis, Gillian Greig, Marie-Claude Mathieu, Kathleen M. Metters, Deborah Slipetz, Robert N. Young

Bioorganic & Medicinal Chemistry Letters · 2003 · 83 citations · 11 references

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11

On the Metabolism of Prostaglandins E1 and E2 in Man

Mats Hámberg, Bengt Samuelsson · Journal of Biological Chemistry · 1971 · 389 citations · Full text

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Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation

Keiji Yoshida, Hiroji Oida, Takuya Kobayashi et al. · Proceedings of the National Academy of Sciences · 2002 · 346 citations

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Impaired Bone Resorption to Prostaglandin E2 in Prostaglandin E Receptor EP4-knockout Mice

Chisato Miyaura, Masaki Inada, Tetsuo Suzawa et al. · Journal of Biological Chemistry · 2000 · 214 citations · Full text

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Prostaglandin Receptor EP<sub>4</sub> Mediates the Bone Anabolic Effects of PGE<sub>2</sub>

M. Machwate, Satoru Harada, Chih‐Tai Leu et al. · Molecular Pharmacology · 2001 · 167 citations

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The effects of prostaglandin E2 in rapidly growing rats: Depressed longitudinal and radial growth and increased metaphyseal hard tissue mass

Keisuke Ueno, T. Haba, D. M. Woodbury et al. · Bone · 1985 · 109 citations

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