Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

Gabriele Bergers, Rolf A. Brekken, Gerald McMahon, +8

Nature Cell Biology

Tumor BiologyAngiogenesisMatrix Metalloproteinase-9 TriggersPathologyVascular Biology +5

MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis

Lisa M. Coussens, Christopher L. Tinkle, Douglas Hanahan, +1

Cell

Skin DevelopmentMedicinePhotocarcinogenesisCancer Cell BiologyStem Cell Research +8

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes.

Mildred Lam, George Dubyak, Liang Chen, +3

Proceedings of the National Academy of Sciences

Ca2+ ReleaseCa2+ FluxesSignal TransductionCell RegulationMedicine +11

Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-κB) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes

Abdelhamid Liacini, Judith Sylvester, Wenqing Li, +1

Matrix Biology

InflammationRheumatologyTranscriptional RegulationCytokineInterleukin-1-stimulated Map Kinases +11

Overexpression of ΔFosB transcription factor(s) increases bone formation and inhibits adipogenesis

G. Sabatakos, Natalie A. Sims, J Chen, +8

Nature Medicine

Transcriptional RegulationDevelopmental BiologyMetabolic RegulationδFosb Transcription FactorBone Formation +6

The Matrix Metalloproteinase-9/Neutrophil Gelatinase-Associated Lipocalin Complex Plays a Role in Breast Tumor Growth and Is Present in the Urine of Breast Cancer Patients

Cecilia A. Fernández, Yan Li, Gwendolyn W. Louis, +3

Clinical Cancer Research

cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype

Leia M. Smith, Scott Wise, Denver T. Hendricks, +5

Oncogene

Breast OncologyCjun OverexpressionMedicineBreast CancerHormone Resistant Phenotype +8

Quercetin inhibition of tumor invasion via suppressing PKC /ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells

C.-W. Lin, Wen‐Chi Hou, Shih-Chieh Shen, +4

Carcinogenesis

Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells

Jitesh Pratap, John J. Wixted, Tripti Gaur, +8

Cancer Research

SclerostinDevelopmental BiologySignaling PathwayBone Morphogenic ProteinMedicine +11

The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9)

Armelle A. Troussard, Penny Costello, Thillainathan Yoganathan, +3

Oncogene

InflammationMatrix Metalloproteinase 9CytokineSignal TransductionSignaling Pathway +10