Lactams as prostanoid receptor ligands. Part 4: 2-Piperidones as selective EP4 receptor agonists

Discovery of a potent and selective agonist of the prostaglandin EP4 receptor

Xavier Billot, Anne Châteauneuf, Nathalie Chauret et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 83 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Optical Enantiomorphs of α-Aminoadipic Acid

Jesse P. Greenstein, Sanford M. Birnbaum, M. Clyde Otey · Journal of the American Chemical Society · 1953 · 49 citations

Natural Sciences, Biochemistry, Chemistry +14

Lactams as EP₄Prostanoid Receptor Agonists. 3. Discovery of<i>N</i>-Ethylbenzoic Acid 2-Pyrrolidinones as Subtype Selective Agents

Todd R. Elworthy, Emma R. Brill, San‐San Chiou et al. · Journal of Medicinal Chemistry · 2004 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Convenient preparations of racemic and enantiopure methyl 6-oxopipecolate

Catherine Davies, Thomas D. Heightman, Stephen A. Hermitage et al. · Synthetic Communications · 1996 · 30 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5

Cyclohexane analogues of the prostaglandins

N.S. Crossley · Tetrahedron Letters · 1971 · 18 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8