Concepedia

Synthesis of functionalized 1,8-naphthyridinones and their evaluation as novel, orally active CB1 receptor inverse agonists

John S. Debenham, Christina B. Madsen-Duggan, Thomas F. Walsh, Junying Wang, Xinchun Tong, George A. Doss, Julie Lao, Tung M. Fong, Marie‐Therese Schaeffer, Jing Chen Xiao,

Bioorganic & Medicinal Chemistry Letters · 2005 · 27 citations · 7 references

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7

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

Murielle Rinaldi‐Carmona, Francis Barth, Michel Héaulme et al. · FEBS Letters · 1994 · 1.8K citations · Full text

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The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis

Daniela Cota, Giovanni Marsicano, Matthias H. Tschöp et al. · Journal of Clinical Investigation · 2003 · 1.1K citations · Full text

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Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice

Andreas Zimmer, Anne Zimmer, Andrea G. Hohmann et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

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Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.

Christian C. Felder, Kelly E. Joyce, Eileen M. Briley et al. · Molecular Pharmacology · 1995 · 879 citations

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Recent advances in CB1 cannabinoid receptor antagonists.

Jos H.M. Lange, Chris G. Kruse · PubMed · 2004 · 40 citations

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