Concepedia

Indinavir analogues with blocked metabolism sites as HIV protease inhibitors with improved pharmacological profiles and high potency against PI-Resistant viral strains

Yuan Cheng, Fengqi Zhang, Thomas A. Rano, Zhijian Lu, William A. Schleif, Lori J. Gabryelski, David B. Olsen, Mark W. Stahlhut, Carrie A. Rutkowski, Jiunn H. Lin,

Bioorganic & Medicinal Chemistry Letters · 2002 · 30 citations · 16 references

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Concepts

References

16

A New Reaction of Nitriles. I. Amides from Alkenes and Mononitriles<sup>1</sup>

John J. Ritter, P. Paul Minieri · Journal of the American Chemical Society · 1948 · 594 citations

, , +4

L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor.

Joseph P. Vacca, Bruce D. Dorsey, William A. Schleif et al. · Proceedings of the National Academy of Sciences · 1994 · 526 citations

, , +17

L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor

Bruce D. Dorsey, Rhonda B. Levin, Joseph P. Vacca et al. · Journal of Medicinal Chemistry · 1994 · 411 citations · Full text

, , +13

Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor

Jon H. Condra, Daniel Holder, William A. Schleif et al. · Journal of Virology · 1996 · 405 citations · Full text

, , +17

Indoles, Benzofurans, Phthalides, and Tolanes via Copper(I) Acetylides

C. E. Castro, E. J. Gaughan, Dennis C. Owsley · The Journal of Organic Chemistry · 1966 · 338 citations

, , +5