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PharmacyMedicinal ChemistryPharmacologyDrug DesignDrug DiscoveryPharmacodynamicsBioactive Small MoleculesDrug-receptor InteractionsLigand BindingMolecular DockingPotency OptimizationReceptor PharmacologyBiological Evaluation ReportImidazole ChemistryImidazole SynthesisMelanocortin SignalingMelanocortin SystemSmall Molecule Drug DesignSmall Molecule Drug Development
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Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice
Dennis Huszar, Catherine Lynch, Victoria Fairchild-Huntress et al. · Cell · 1997 · 3K citations · Full text
Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor
Dongsi Lu, Derril H. Willard, Indravadan R. Patel et al. · Nature · 1994 · 1.1K citations
Cancer anorexia-cachexia syndrome: are neuropeptides the key?
Akio Inui · PubMed · 1999 · 345 citations
Life Sciences, Oncology, Physiology +17
Role of the central melanocortin system in cachexia.
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