Synthesis of a novel bridged nucleoside bearing a fused-azetidine ring, 3′-amino-3′,4′-BNA monomer

LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition

Sanjay K. Singh, Alexei A. Koshkin, Jesper Wengel et al. · Chemical Communications · 1998 · 770 citations

Life Sciences, Biotechnology, Molecular Biology +16

Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides

Satoshi Obika, Daishu Nanbu, Yoshiyuki Hari et al. · Tetrahedron Letters · 1998 · 693 citations

Life Sciences, Chemistry, Molecular Biology +16

Sequence‐Specific Recognition and Modification of Double‐Helical DNA by Oligonucleotides

Nguyen T. Thuong, Claude Hélène · Angewandte Chemie International Edition in English · 1993 · 624 citations

Life Sciences, Biochemistry, Molecular Biology +15

Synthesis of 2′-O,4′-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed C3, -endo sugar puckering

Satoshi Obika, Daishu Nanbu, Yoshiyuki Hari et al. · Tetrahedron Letters · 1997 · 601 citations

Natural Sciences, Biochemistry, Chemistry +13

Synthesis of 3‘-<i>C</i>- and 4‘-<i>C</i>-Branched Oligodeoxynucleotides and the Development of Locked Nucleic Acid (LNA)

Jesper Wengel · Accounts of Chemical Research · 1998 · 334 citations

Pharmacy, Biochemistry, Chemistry +12