Highly sensitive and selective detection of human carboxylesterase 1 activity by liquid chromatography with fluorescence detection

Structure, function and regulation of carboxylesterases

Masakiyo Hosokawa · Chemico-Biological Interactions · 2006 · 483 citations

Life Sciences, Biochemistry, Molecular Biology +3

Current Progress on Esterases: From Molecular Structure to Function

Tetsuo Satoh, Palmer Taylor, William Bosron et al. · Drug Metabolism and Disposition · 2002 · 293 citations

Life Sciences, Biochemistry, Pharmacology +17

Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan.

Guang Xu, Wanghai Zhang, Howard L. McLeod · PubMed · 2002 · 278 citations

Medicine, Cancer Biology, Pharmacology +12

Anti-Influenza Prodrug Oseltamivir Is Activated by Carboxylesterase Human Carboxylesterase 1, and the Activation Is Inhibited by Antiplatelet Agent Clopidogrel

Deshi Shi, Jian Yang, Dongfang Yang et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 277 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Methylphenidate Is Stereoselectively Hydrolyzed by Human Carboxylesterase CES1A1

Zejin Sun, Daryl J. Murry, Sonal P. Sanghani et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 186 citations

Medicine, Pharmacokinetics, Pharmacology +15