Leptin deficiency produces contrasting phenotypes in bones of the limb and spine

Leptin Inhibits Bone Formation through a Hypothalamic Relay

Patricia Ducy, Michael Amling, Shu Takeda et al. · Cell · 2000 · 2.1K citations · Full text

Medicine, Endocrinology, Physiology +13

Transforming growth factor beta

Anita B. Roberts, Michael B. Sporn · SpringerReference · 2011 · 1.9K citations

Medicine, Ophthalmology, Surgery +16

Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis

J. Justesen, Karin Stenderup, E.N. Ebbesen et al. · Biogerontology · 2001 · 843 citations

Medicine, Endocrinology, Orthopedic Surgery +14

Osteoporosis and the Replacement of Cell Populations of the Marrow by Adipose Tissue

Pierre J. Meunier, J. Aaron, C Edouard et al. · Clinical Orthopaedics and Related Research · 1971 · 790 citations

Medicine, Endocrinology, Orthopedic Surgery +17

Leptin Acts on Human Marrow Stromal Cells to Enhance Differentiation to Osteoblasts and to Inhibit Differentiation to Adipocytes¹

Thierry Thomas, Francesca Gori, Sundeep Khosla et al. · Endocrinology · 1999 · 720 citations · Full text

Medicine, Endocrinology, Physiology +17