Concepedia

Publication | Open Access

Targeting Aurora Kinase with MK-0457 Inhibits Ovarian Cancer Growth

DOIFull Paper Access

63

Citations

38

References

2008

Year

Yvonne G. Lin, Anand Immaneni, William M. Merritt, Lingegowda S. Mangala, Seung Wook Kim, Mian M.K. Shahzad, Yvonne T.M. Tsang, Guillermo N. Armaiz-Peña, Chunhua Lu, Aparna A. Kamat,
Clinical Cancer Research

Abstract

Aurora kinase inhibition significantly reduces tumor burden and cell proliferation and increases tumor cell apoptosis in this preclinical orthotopic model of ovarian cancer. The role of Aurora kinase inhibition in ovarian cancer merits further investigation in clinical trials.

References

YearCitations

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