Regulation of Protein Kinase C-related Protein Kinase 2 (PRK2) by an Intermolecular PRK2-PRK2 Interaction Mediated by Its N-terminal Domain

An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor

Xuewu Zhang, Jodi Gureasko, Kui Shen et al. · Cell · 2006 · 1.6K citations · Full text

Kinase Domain, Developmental Biology, Signal Transduction +8

The PI3K–PDK1 connection: more than just a road to PKB

Bart Vanhaesebroeck, Dario R. Alessi · Biochemical Journal · 2000 · 1.6K citations · Full text

Direct Regulation of the <i>Akt</i> Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

T. Franke, David R. Kaplan, Lewis C. Cantley et al. · Science · 1997 · 1.5K citations

High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

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Viral Replication, Immunology, Transient Transfection +18

Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

Daniel R. Knighton, Jianhua Zheng, Lynn F. Ten Eyck et al. · Science · 1991 · 961 citations

Protein Assembly, Molecular Biology, Peptide Inhibitor Bound +18