Characterization of ISRgn <i>1</i> , a Novel Insertion Sequence of the IS <i>3</i> Family Isolated from a Bacteriocin-Negative Mutant of <i>Ruminococcus gnavus</i> E1

Abstract

ISRgn1, an insertion sequence of the IS3 family, has been identified in the genome of a bacteriocin-negative mutant of Ruminococcus gnavus E1. The copy number of ISRgn1 in R. gnavus E1, as well as its distribution among phylogenetically E1-related strains, has been determined. Results obtained suggest that ISRgn1 is not indigenous to the R. gnavus phylogenetic group but that it can transpose in this bacterium.