Concepedia

Anti-miR-33 Therapy Does Not Alter the Progression of Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

Tyler J. Marquart, Judy Wu, Aldons J. Lusis, Ángel Baldán

Arteriosclerosis Thrombosis and Vascular Biology · 2013 · 106 citations · 13 references

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Abstract

Prolonged silencing of miR-33 fails to maintain elevated plasma high-density lipoprotein cholesterol and does not prevent the progression of atherosclerosis in Ldlr(-/-) mice.

References

13

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

Katey J. Rayner, Yajaira Suárez, Alberto Dávalos et al. · Science · 2010 · 1.2K citations · Full text

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MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

S. Hani Najafi‐Shoushtari, Fjoralba Kristo, Yingxia Li et al. · Science · 2010 · 932 citations · Full text

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Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

Katey J. Rayner, Christine Esau, Farah Hussain et al. · Nature · 2011 · 692 citations · Full text

, , +13

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

Katey J. Rayner, Frederick J. Sheedy, Christine Esau et al. · Journal of Clinical Investigation · 2011 · 679 citations

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

Alberto Dávalos, Leigh Goedeke, Peter Smibert et al. · Proceedings of the National Academy of Sciences · 2011 · 658 citations · Full text