Extrusion improved the anti‐inflammatory effect of amaranth (<i><scp>A</scp>maranthus hypochondriacus</i>) hydrolysates in <scp>LPS</scp>‐induced human <scp>THP</scp>‐1 macrophage‐like and mouse <scp>RAW</scp> 264.7 macrophages by preventing activation of <scp>NF</scp>‐κ<scp>B</scp> signaling

Abstract

Amaranth hydrolysates inhibited LPS-induced inflammation in human and mouse macrophages by preventing activation of NF-κB signaling. Extrusion improved anti-inflammatory effect of amaranth hydrolysates in both cells, which might be attributed to the production of bioactive peptides during processing.