Genetically engineered mouse models and human osteosarcoma

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Mark F. Pittenger, Alastair M. Mackay, Stephen C. Beck et al. · Science · 1999 · 20.9K citations

Adult Stem Cell, Multilineage Potential, Biomedical Engineering +16

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

David Malkin, Frederick P. Li, Louise C. Strong et al. · Science · 1990 · 3.8K citations

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COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

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Osteosarcoma incidence and survival rates from 1973 to 2004

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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

Chu‐Xia Deng, Pumin Zhang, J. Wade Harper et al. · Cell · 1995 · 2.1K citations · Full text

Knockout Mouse, Genome Instability, Developmental Biology +8