Macrophage cholesterol efflux correlates with lipoprotein subclass distribution and risk of obstructive coronary artery disease in patients undergoing coronary angiography

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

Angela Brooks‐Wilson, Michel Marcil, Susanne M. Clee et al. · Nature Genetics · 1999 · 1.7K citations

Mendelian Disorder, Disease Mechanism, Genetic Disorder +13

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

Marek Bodzioch, Evelyn Orsó, Jochen Klucken et al. · Nature Genetics · 1999 · 1.5K citations

Disease Mechanism, Natural Sciences, Genetics +6

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

Stephan Rust, Marie Rosier, Harald Funke et al. · Nature Genetics · 1999 · 1.4K citations

Signal Transduction, Disease Mechanism, Genetic Disorder +6

Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

Jenelle M. Timmins, Elena Boudyguina, Kimberly D. Kluckman et al. · Journal of Clinical Investigation · 2005 · 445 citations

Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease.

Gordon A. Francis, Robert H. Knopp, John F. Oram · Journal of Clinical Investigation · 1995 · 420 citations · Full text

Lipid Disorder, Oxysterol, Allergy +14