Angewandte Chemie International Edition · 1998 · 33 citations · 0 references
Natural SciencesBiochemistryChemistryCatalysisCatalytic MechanismsCross-coupling ReactionsEnzyme-substrate RecognitionAldol AdditionAldol ReactionKetone FunctionalizationKetonesStereoselective Aldol Reactions
A new concept for one-pot reactions! Different functional groups in substrates undergo separate reactions simultaneously (depicted schematically below). A practical application is described for the (C6H5)2SnBr2-catalyzed Mukaiyama aldol reaction of ketones and acetals.