Evaluation of HepaRG Cells as an in Vitro Model for Human Drug Metabolism Studies

EXPRESSION OF CYTOCHROMES P450, CONJUGATING ENZYMES AND NUCLEAR RECEPTORS IN HUMAN HEPATOMA HepaRG CELLS

Caroline Aninat, Amélie Piton, Denise Glaise et al. · Drug Metabolism and Disposition · 2005 · 678 citations

Medicine, Cell Biology, Molecular Biology +13

Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily

Jack Gorski, Stephen D. Hall, D. I. Jones et al. · Biochemical Pharmacology · 1994 · 397 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Transdifferentiation of hepatocyte‐like cells from the human hepatoma HepaRG cell line through bipotent progenitor†

Virginie Cérec, Denise Glaise, Delphine Garnier et al. · Hepatology · 2007 · 350 citations · Full text

Medicine, Cell Biology, Pathology +17

Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes

Ajay Madan, Richard Graham, Kathleen Carroll et al. · Drug Metabolism and Disposition · 2003 · 337 citations

Medicine, Biochemistry, Pharmacology +17

Human CYP2B6: expression, inducibility and catalytic activities.

Laurence Gervot, Bertrand Rochat, Jean‐Charles Gautier et al. · PubMed · 1999 · 245 citations

Medicine, Biochemistry, Molecular Biology +17