Hypoxia and hypoxia-inducible factor-1α provoke toll-like receptor signalling-induced inflammation in rheumatoid arthritis

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov et al. · Nature · 2001 · 6.1K citations

Life Sciences, Immunology, Molecular Biology +14

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Daniel J. Ceradini, Anita R. Kulkarni, Matthew J. Callaghan et al. · Nature Medicine · 2004 · 2.6K citations

Life Sciences, Cell Biology, Molecular Biology +14

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

Jordi Rius, Mónica Gumá, Christian Schachtrup et al. · Nature · 2008 · 1.6K citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

Eric V. Dang, Joseph Barbi, Huang‐Yu Yang et al. · Cell · 2011 · 1.6K citations · Full text

Life Sciences, Cell Biology, Immunology +13

RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via toll‐like receptor 3

Fabia Brentano, Olivier Schorr, Renate E. Gay et al. · Arthritis & Rheumatism · 2005 · 370 citations

Life Sciences, Immunology, Pathobiology +12