A simple, rapid, and sensitive system for the evaluation of anti-viral drugs in rats

Identification of a major co-receptor for primary isolates of HIV-1

Hongkui Deng, Rong Liu, Wilfried Ellmeier et al. · Nature · 1996 · 3.7K citations

Life Sciences, Infectious Diseases, Molecular Biology +11

Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity

Patrick Dorr, Mike Westby, Susan Dobbs et al. · Antimicrobial Agents and Chemotherapy · 2005 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection.

Carl Wild, D C Shugars, Teresa Greenwell et al. · Proceedings of the National Academy of Sciences · 1994 · 933 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene

J S Kimpton, Michael Emerman · Journal of Virology · 1992 · 916 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

Enfuvirtide, an HIV-1 Fusion Inhibitor, for Drug-Resistant HIV Infection in North and South America

Jacob Lalezari, Keith Henry, Mary O’Hearn et al. · New England Journal of Medicine · 2003 · 915 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacotherapy +16