Region-Specific Overexpression of P-glycoprotein at the Blood-Brain Barrier Affects Brain Uptake of Phenytoin in Epileptic Rats

Measurement of protein using bicinchoninic acid

Pam Smith, Randall I. Krohn, Greg T. Hermanson et al. · Analytical Biochemistry · 1985 · 18.2K citations

Protein Chemistry, Bicinchoninic Acid, Biochemistry +5

Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy

Erwin A. van Vliet, S. da Costa Araújo, Sandra Redeker et al. · Brain · 2006 · 764 citations

Neuropsychology, Bbb Permeability, Temporal Lobe Epilepsy +22

<i>MDR1</i> Gene Expression in Brain of Patients with Medically Intractable Epilepsy

David M. Tishler, Kenneth I. Weinberg, David R. Hinton et al. · Epilepsia · 1995 · 529 citations

Neurogenomics, Genetics, Neurochemical Biomarkers +18

In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576.

Prakash Mistry, Alistair Stewart, Wendy Dangerfield et al. · PubMed · 2001 · 350 citations

Pharmacotherapy, Tumor Biology, P-glycoprotein-mediated Multidrug Resistance +17

Xenobiotic Transport across Isolated Brain Microvessels Studied by Confocal Microscopy

David S. Miller, Stephanie Nobmann, Heike Gutmann et al. · Molecular Pharmacology · 2000 · 305 citations