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Extracellular ATP Is a Danger Signal Activating P2X <sub>7</sub> Receptor in Lung Inflammation and Fibrosis

DOI

397

Citations

39

References

2010

Year

Nicolas Riteau, Paméla Gasse, Louis Fauconnier, Aurélie Gombault, Marion Couegnat, Lizette Fick, Jean Kanellopoulos, Valérie Quesniaux, S. Marchand‐Adam, Bruno Crestani,
American Journal of Respiratory and Critical Care Medicine

Abstract

ATP released from BLM-injured lung cells constitutes a major endogenous danger signal that engages the P2X(7) receptor/pannexin-1 axis, leading to IL-1β maturation and lung fibrosis.

References

YearCitations

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