Concepedia

β-Lactamase inhibition by avibactam in <i>Mycobacterium abscessus</i>

Vincent Dubée, Audrey Bernut, Mélanie Cortès, Tiffany Lesne, Delphine Dorchêne, Anne-Laure Lefebvre, Jean‐Emmanuel Hugonnet, Laurent Gutmann, Jean‐Luc Mainardi, Jean‐Louis Herrmann,

Journal of Antimicrobial Chemotherapy · 2014 · 160 citations · 37 references

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Abstract

Our data identify avibactam as the first efficient inhibitor of BlaMab and strongly suggest that β-lactamase inhibition should be evaluated to provide improved therapeutic options for M. abscessus infections.

References

37

A Novel Gene, <i>erm</i> (41), Confers Inducible Macrolide Resistance to Clinical Isolates of <i>Mycobacterium abscessus</i> but Is Absent from <i>Mycobacterium chelonae</i>

Kevin A. Nash, Barbara A. Brown‐Elliott, Richard J. Wallace · Antimicrobial Agents and Chemotherapy · 2009 · 636 citations · Full text

Clinical Features of Pulmonary Disease Caused by Rapidly Growing Mycobacteria: An Analysis of 154 Patients

David E. Griffith, William M. Girard, Richard J. Wallace · American Review of Respiratory Disease · 1993 · 512 citations

, , +16

Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor

David E. Ehmann, Haris Jahić, Philip L. Ross et al. · Proceedings of the National Academy of Sciences · 2012 · 507 citations · Full text

Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant <i>Mycobacterium tuberculosis</i>

Jean‐Emmanuel Hugonnet, L.W. Tremblay, Helena I. Boshoff et al. · Science · 2009 · 492 citations · Full text

, , +15

Emergence of Communication Networks

Peter R. Monge, Noshir Contractor · 2001 · 393 citations

, , +6