O<sup>6</sup>-Methylguanine-DNA Methyltransferase Expression Strongly Correlates With Outcome in Childhood Malignant Gliomas: Results From the CCG-945 Cohort - Concepedia

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O<sup>6</sup>-Methylguanine-DNA Methyltransferase Expression Strongly Correlates With Outcome in Childhood Malignant Gliomas: Results From the CCG-945 Cohort

DOI Full Paper Access

173

Citations

50

References

2006

Year

Ian F. Pollack, Ronald L. Hamilton, Robert W. Sobol, Judith Burnham, Allan J. Yates, Emiko J. Holmes, Tianni Zhou, Jonathan L. Finlay

Journal of Clinical Oncology

Abstract

Overexpression of MGMT in childhood malignant gliomas is strongly associated with an adverse outcome in children treated with alkylator-based chemotherapy, independently of a variety of clinical prognostic factors.

References

	Year	Citations

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