Effects of repeated ingestion of grapefruit juice on the single and multiple oral-dose pharmacokinetics and pharmacodynamics of alprazolam

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The UKU side effect rating scale: A new comprehensive rating scale for psychotropic drugs and a cross‐sectional study of side effects in neuroleptic‐treated patients

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Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*

Kenneth S. Lown, Robert R. Mayo, Alan B. Leichtman et al. · Clinical Pharmacology & Therapeutics · 1997 · 682 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.

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CYP3A gene expression in human gut epithelium

Joseph C. Kolars, Kenneth S. Lown, Phyllissa Schmiedlin‐Ren et al. · Pharmacogenetics · 1994 · 369 citations

Life Sciences, Biochemistry, Molecular Biology +11