Neutrophil Extracellular Traps Kill Bacteria

Volker Brinkmann, Ulrike Reichard, Christian Goosmann, +5

Science

InflammationBacterial InfectionsMicrobial PathogensSpontaneous Human AppendicitisVirulence Factor +12

Novel cell death program leads to neutrophil extracellular traps

Tobias A. Fuchs, Ulrike Abu Abed, Christian Goosmann, +6

The Journal of Cell Biology

Nadph OxidaseApoptosisImmunologyCell DeathGranule Proteins +15

Extracellular DNA traps promote thrombosis

Tobias A. Fuchs, Alexander Brill, Daniel Duerschmied, +7

Proceedings of the National Academy of Sciences

GeneticsImmunologyBlood CellPathologyInnate Immunity +20

Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

Stephen Clark, C. Adrienne, Samantha A. Tavener, +13

Nature Medicine

InflammationToll-like ReceptorsNeutrophil Extracellular TrapsGranulocyteVirulence Factor +10

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

Marie-Luise von Brühl, Konstantin Stark, Alexander Steinhart, +28

The Journal of Experimental Medicine

Deep Vein ThrombosisImmunologyImmune RegulationCell DeathPathology +20

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

Constantin F. Urban, David Ermert, Monika Schmid, +6

PLoS Pathogens

Antimicrobial Heterodimer CalprotectinFungal Cell BiologyInnate Immune SystemImmunologyInnate Immunity +14

The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β

Min-Jean Yin, Yumi Yamamoto, Richard B. Gaynor

Nature

InflammationCytokineAnti-inflammatoryAnti-inflammatory AgentsSignal Transduction +8

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

Abdul Hakkim, Barbara G. Fürnrohr, Kerstin Amann, +6

Proceedings of the National Academy of Sciences

Glomerular DiseaseImmunologyPathologyImmunotherapySle Patients +16

Novel Inhibitors of Cytokine-induced IκBα Phosphorylation and Endothelial Cell Adhesion Molecule Expression Show Anti-inflammatory Effects in Vivo

Jacqueline W. Pierce, Robert Schoenleber, Gary Jesmok, +4

Journal of Biological Chemistry

Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms

Constantin F. Urban, Ulrike Reichard, Volker Brinkmann, +1

Cellular Microbiology

Neutrophils TrapAntifungal AgentMicrobial PathogensFungal Cell BiologyCandida Albicans +13