In vivo detection and quantification of chemicals that enhance protein stability

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes

Ulrich S. Schubert, Luis C. Antón, James S. Gibbs et al. · Nature · 2000 · 1.5K citations

Life Sciences, Biochemistry, Molecular Biology +13

A molecular mechanism for osmolyte-induced protein stability

Timothy O. Street, D. Wayne Bolen, George D. Rose · Proceedings of the National Academy of Sciences · 2006 · 679 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

Mechanisms of Protein Stabilization and Prevention of Protein Aggregation by Glycerol

Vincent Vagenende, Miranda G.S. Yap, Bernhardt L. Trout · Biochemistry · 2009 · 526 citations

Natural Sciences, Biochemistry, Biophysics +17

β-Lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein–protein interactions

André Galarneau, Martin Primeau, Louis‐Éric Trudeau et al. · Nature Biotechnology · 2002 · 409 citations

Life Sciences, Biochemistry, Molecular Biology +12

Im7 folding mechanism: misfolding on a path to the native state

Andrew P. Capaldi, Colin Kleanthous, Sheena E. Radford · Nature Structural Biology · 2002 · 249 citations

Life Sciences, Biophysics, Molecular Biology +12