Clinical Chemistry · 2001 · 27 citations · 13 references
MedicinePharmacologyAnalytical ToxicologyClinical BiochemistryClinical PharmacologyBioanalytical Method ValidationOpioid PharmacologyProstate-specific Antigen TestingConcentrationMulticenter ValidationPercent Free Prostate-specific AntigenPrecisionProstate-specific Antigen Cutoff ValuesTarget Concentration DeterminationTotal Drug ConcentrationsUrine Opioid Testing
g/L cutoff was determined monthly using data obtained from daily analysis of samples with target concentrations of 240 and 360 g/L. Representative (most recent) CVs at these concentrations were as follows: 3.8% and 3.1% for codeine, 3.9% and 3.2% for morphine, 3.3% and 3.6% for hydrocodone, 3.2% and 3.9% for hydromorphone, and 4.4% and 4.5% for oxycodone, respectively.
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